APSCO is the first extensive interdisciplinary research project in Romania focusing on psychosocial aspects of cancer in oncology institutions, in supportive care groups and in palliative services, including data from multi-centre questionnaire screening, survey and multivariate data analysis. The basic aim of APSCO research is to explore and examine cancer-related distress and quality of life, with specifics of cancer diagnosis disclosure in Romania. Therefore, understanding cancer distress, quality of life and communication needs in Romanian cancer patients can lead to a better understanding of factors needed to develop and use psychosocial services in Romanian oncology settings.